George Patrinos, Wilhelm Ansorge - Molecular Diagnostics, Second Edition - Diagnóstico Molecular, 2ª Edición Links actualizados

George Patrinos, Wilhelm Ansorge - Molecular Diagnostics, Second Edition - Diagnóstico Molecular, 2ª Edición

Academic Press | ISBN: 0123745373 | 2009-10-07 | PDF | 616 pages | 8.98 Mb

The second edition of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2/e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2/e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics; professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as, academic institutions and hospital libraries.

- Contains state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders
- Includes in-depth discussion of ethical and safety considerations
- Identifies genetically modified organisms (GMO's)
- Covers forensic analysis and every-day issues in a diagnostic laboratory
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Robert Weaver, "Molecular Biology" 5 edition 2011- Robert Weaver, "Biología Molecular" (2011)

Robert Weaver, "Molecular Biology"- Robert Weaver, "Biología Molecular" (2011)

Publisher: McGraw-Hill Science/Engineering/Math; 5 edition | ISBN 10: 0073525324 | 2011 | PDF | 912 pages | 40.9 MB

Molecular Biology, 4/e by Robert Weaver, is designed for an introductory course in molecular biology. Molecular Biology 5/e focuses on the fundamental concepts of molecular biology emphasizing experimentation. In particular author, Rob Weaver, focuses on the study of genes and their activities at the molecular level. Through the combination of excellent illustrations and clear, succinct writing students are presented fundamental molecular biology concepts.

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Anna M. Wobus, Kenneth R. Boheler - Stem Cells Links actualizados

Anna M. Wobus, Kenneth R. Boheler - Stem Cells

Publisher: Sрringer | 2005-12-21 | ISBN: 3540261338 | PDF | 414 pages | 4.14 MB

During the past few years, stem cell research has metamorphosed into distinct and specialized avenues of research. However, the present book presents in a single volume many novel aspects of stem cell biology with respect to scientific endeavours and future applications. Of particular note is the coverage of the pharmacological issues which have never been adequately addressed in the past.
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Concepts of Genetics (9th Edition) by William S. Klug- Conceptos de Genética (9ª Edición) por William S. Klug

Concepts of Genetics (9th Edition) by William S. Klug - Conceptos de Genética (9ª Edición) por William S. Klug

Benjamin Cummings | ISBN : 0321524047 | February 16, 2008 | 899 pages | PDF | 61MB
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Kreitzer Geri, Julio E. Celis, "Cell Biology Assays: Essential Methods" - "Ensayos en Biología Celular: Métodos Esenciales" Links actualizados

Kreitzer Geri, Julio E. Celis, "Cell Biology Assays: Essential Methods" - "Ensayos en Biología Celular: Métodos Esenciales"

Academic Press | 2009-11-20 | ISBN: 0123751527 | 298 pages | PDF | 2,2 MB 

Cell Biology Assays: Essential methods presents a comprehensive overview of protocols essential for researchers.. Chapters provide clear explanations, step-by-step instruction, tips and potential pitfalls. The important steps and results are illustrated for further ease of use. This text enables researchers at various career levels a plethera of insight into technologies and model systems in biological problem solving. # Provids researchers with solutions in lab enviornments # Features an array of essential methods including endocytic pathways, membranes, mitochondria, and vitro motility # Information on a plethora of technologies needed to tackle complex problem
 

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The Cell: A Molecular Approach, Fourth Edition By Geoffrey M. Cooper, Robert E. Hausman - La Célula Enfoque Molecular 4ª Edición Cooper, Hausman

The Cell: A Molecular Approach, Fourth Edition By Geoffrey M. Cooper, Robert E. Hausman - La Célula Enfoque Molecular 4ª Edición Cooper, Hausman

Publisher: Sinauer Associates, Inc.
Number Of Pages: 745
Publication Date: 2006-06-01
ISBN-10 / ASIN: 0878932194
ISBN-13 / EAN: 9780878932191
Product Description:
Courses in molecular and cellular biology are a cornerstone of undergraduate programs in the life sciences. The material is not only fundamental to all of biology, but also represents an exciting and rapidly moving area of science. This makes teaching undergraduates a rewarding experience, but also a challenging task. The Cell: A Molecular Approach meets this challenge by providing students with not only the most current information, but also with a conceptual framework and an introduction to the experimental nature of contemporary research. Designed for use in one-semester introductory cell biology courses, The Cell presents current comprehensive science in a readable and cohesive text that students can master in the course of one semester.
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Biophysical Labeling Methods in Molecular BiologyMétodos Biofísicos de Marcación en Biología Molecular 

Cambridge University Press | 22 de agosto 2005 | ISBN-10: 0521017874 | 320 páginas | PDF | 15.44 MB

Esta monografía describe las bases teóricas y requisitos para los métodos experimentales como la fluorescencia de la vuelta, las moléculas biológicas triplete, Mössbauer, fotosensibles y de densidad electrónica de etiquetado, incluyendo los procedimientos utilizados para obtener las proteínas específicamente modificados, enzimas, biomembranas, ácidos nucleicos, y otros. Los fundamentos de la teoría de la física detrás de cada técnica se explica y se dan detalles sobre cómo interpretar los datos experimentales obtenidos. secciones especiales sobre los estudios críticos de los últimos datos sobre la estructura, dinámica molecular y las transiciones conformacionales de las moléculas biológicas. Cada sección concluye con una discusión de los resultados obtenidos a partir de estas técnicas en relación con diversos problemas de la catálisis enzimática, la transferencia de electrones, la biofísica molecular y biología molecular. Los usos que las técnicas de etiquetado se puede poner a la investigación de células y tejidos se discuten también.

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Mouse Cell Culture: Methods and Protocols (Methods in Molecular Biology)

Mouse Cell Culture: Methods and Protocols (Methods in Molecular Biology)

Humana Press 2010 | 250 | ISBN: 1588297721 | PDF | 4 MB

Cultured cells have combined accessibility and the ability to expand a homogeneous cell population from a relatively limited source, thus opening up a wealth of possibilities for researchers. In Mouse Cell Culture: Methods and Protocols, expert researchers provide a number of methods for the culture of a wide range of specific cells and tissues isolated from the key genetic model of the fetal or adult mouse. Including protocols for the explant of fetal tissues and stem cells that allow developmental processes to be followed ex vivo as well as protocols for the culture of isolated cell types that allow for the study of relatively homogeneous cell populations, this volume brings together a selection of the most current methods in order to make them available in one convenient source. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls....... 
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Molecular Biology of the Gene (with CD) - Biología Molecular del Gen (Con CD)

Molecular Biology of the Gene (with CD) - Biología Molecular del Gen (Con CD)

2003 | 755 | ISBN: 0321223683 | PDF | 21 + 67 Mb

DJVUThis revised text contains 21 chapters co-authored by five molecular biologists and provides authoritative coverage of a fast-changing discipline. Included is balanced coverage of prokaryotic and eukaryotic systems and information on important experiments and techniques.......  

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Cell and Molecular Biology Concepts and Experiments (6th Edition) - Gerald Karp, Biología Molecular y Celular: Conceptos y Experimentos (6ª Edición) libro y CD links actualizados

Cell and Molecular Biology: Concepts and Experiments (6th Edition) by Gerald Karp - Biología Molecular y Celular: Conceptos y Experimentos (6ª Edición) Publisher: Wiley; 6 edition | Price from Amazon:$128.00 | ISBN: 0470483377 | October 20, 2009 | 832 Pages | PDF | 101MB Se entrega CD acompañante (36 MB) Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with 揤IP?art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection.   Libro más CD acompañante (2 en 1):  mediadescarga aquí mediadescarga aquí (Mirror)  Mirrors:  ziddu / 4shared / 1fichier / jumbofiles / 2shared     / zippyshare / uptobox / crocko  Enlace de descarga del karp CD acompañante ( sólo, sin pass): mediadescarga aquí mediadescarga aquí (Mirror) Mirrors: zippyshare / crocko / uptobox / 2shared / depositfiles  / zshare / jumbofiles / ziddu / 1fichier 4shadescarga aquí libro pass: www.fomscu-forum.com

Bacteriophages: Methods and Protocols, Volume 2: Molecular and Applied Aspects (2008)

 Bacteriophages: Methods and Protocols, Volume 2: Molecular and Applied Aspects - Bacteriófagos: Métodos y Protocolos, Volumen 2: Aspectos Moleculares y Aplicados

Martha R.J. Clokie, Andrew M. Kropinski; Tamaño: 6 MB; PDF (English)

Description: Ranging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community. Bacteriophages: Methods and Protocols pulls together the vast body of knowledge and expertise from top international bacteriophage researchers to provide both classical and state-of-the-art molecular techniques. With its well-organized modular design, Volume 2: Molecular and Applied Aspects examines a multitude of topics, including the bacteriophage genomics, metagenomics, transcriptomics, and proteomics, along with applied bacteriophage biology. Written in the highly successful Methods in Molecular Biology™ series format, chapters consist of brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section which details tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Bacteriophages: Methods and Protocols is a valuable reference for experienced bacteriophage researchers as well as an easily accessible introduction for newcomers to the subject.  Este es un excelente libro sobre bacteriófagos muy bueno realmente.

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The Chaperonins (Cell Biology)

The Chaperonins (Cell Biology) by Robert L. Ellis

Publisher: Academic Press (March 22, 1996) | ISBN: 012237455X | Pages: 323 | PDF | 19.05 MB

The first of its kind, this volume presents the latest research findings on the chaperonins, the best studied family of a class of proteins known as molecular chaperones. These findings are changing our view of some fundamental cellular processes involving proteins, especially how proteins fold into their functional conformations.

Key Features
* Origins of the new view of protein folding
* Prokaryotic chaperonins
* Eukaryotic chaperonins
* Evolution of the chaperonins
* Refolding of denatured proteins
* Organelle biosynthesis
* Biomedical aspects

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Virus Oncogénicos Humanos (2ª Edición) - Human Oncogenic Viruses (2nd Edition)

Jing-hsuin James Ou, T. S. Benedict Yen - Human Oncogenic Viruses (2nd Edition) - Virus Oncogénicos Humanos (2ª Edición)

World Scientific Publishing Company | ISBN: 9812833463 | 2009-12-21 | PDF | 352 pages | 7.17 Mb

Viruses are the causes of approximately 25 per cent of human cancers. Due to their importance in carcinogenesis, there is a desperate need for a book that discusses these viruses. This book is therefore timely, providing a comprehensive review of the molecular biology of oncogenic viruses and the cancers they cause. Viruses that are discussed in the individual chapters include hepatitis B virus, hepatitis C virus, human papilloma viruses, Epstein-Barr virus, Kaposi's sarcoma virus and human T-cell leukemia virus type 1. This book provides up-to-date information for graduate students, postdoctoral fellows, medical students, physicians and non-experts who are interested in learning more about the oncogenic viruses and how they cause human cancers.
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Diagnóstico Molecular de las Enfermedades Infecciosas - Harald Kessler, Molecular Diagnostics of Infectious Diseases

Harald Kessler, "Molecular Diagnostics of Infectious Diseases"- Diagnóstico Molecular de las Enfermedades Infecciosas

De Gruyter | 2010 | ISBN: 3110214857, 3110214865 | 250 pages | PDF | 1,2 MB

Molecular diagnostics has become one of the dominant platforms in clinical laboratory
medicine. In recent years, the advent of molecular methods has revolutionized the
evaluation of patients with presumed infectious diseases. Molecular methods not only
evaluate patients with infectious diseases but also contribute to the use of therapeutic
modalities in their treatment and cure.
Molecular diagnostics based on the direct detection of specific genetic material
in a specimen through nucleic acid amplification techniques (NATs) has largely
replaced antigen testing by immunoassays and become the leading technology. The
new molecular test systems are more specific and sensitive. They are able to detect
the presence of a pathogen faster than immunoassays. Furthermore, NATs provide the
possibility for detection of genetic variations allowing for further characterization of
pathogens including geno- and subtypes and drug-resistant variants.
Today, improved molecular diagnostics instrumentation automates many of the
sample preparation and assay steps that were formerly labor intensive. Robust chemistries
allow continual launch of new molecular assays with the majority of them being
CE-marked and/or FDA-cleared. Consequently, molecular diagnostics is indicated in
many areas of healthcare including infectious diseases, hematology/oncology, genetic
disorders and forensic medicine with molecular diagnostics of infectious diseases
making up the major part of the molecular in vitro diagnostics (IVD) market.
This book is intended to give a timely overview of molecular diagnostics of infectious
diseases. In the general section (chapters 1–6), preanalytical, analytical and postanalytical
issues are discussed. Furthermore, special attention is drawn to quality assurance/
quality control issues. In the specialized section (chapters 7–13), NATs for detection of
pathogens producing infectious diseases are discussed in detail. Each chapter focuses
on infectious diseases targeting a specific body tract or system. In all, this book can be
used as a starting point to evaluate which molecular method, test system, or instrument
may be considered or chosen for diagnostics of infectious diseases.
Molecular Diagnostics of Infectious Diseases tries to cover the whole field and provides
the utmost timely content. However, the reader should consider that this field is still
changing rapidly. Suggestions for further improvements to be considered in a future edition
are highly appreciated. Please contact the editor at harald.kessler@medunigraz.at.
Harald H. Kessler

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Assay Development: Fundamentals and Practices - Desarrollo de un Ensayo: Fundamentos y Prácticas

Ge Wu, "Assay Development: Fundamentals and Practices" - Desarrollo de un Ensayo: Fundamentos y Prácticas

Wiley | 2010 | ISBN: 0470191155, 0470583118 | 429 pages | PDF | 5,2 MB

Essential principles and practice of assay development
The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting.
Rather than attempting comprehensive coverage of all assay development technologies, the book introduces the most widely used assay development technologies and illustrates the art of assay development through a few commonly encountered biological targets in assay development (e.g., proteases, kinases, ion channels, and G protein-coupled receptors). Just enough biological background for these biological targets is provided so that the reader can follow the logics of assay development. Chapters discuss:
•The basics of assay development, including foundational concepts and applications
•Commonly used instrumental methods for both biochemical assays and cell-based assays
•Assay strategies for protein binding and enzymatic activity
•Cell-based assays
•High-throughput screening
An in-depth study of the now popular Caliper's off-chip kinase assay provides an instructive, real-world example of the assay development process.

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Regulación del Ciclo Celular y la Diferenciación en los Sistemas Cardiovascular y Neuronales - Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems By Antonio Giordano, Umberto Galderisi

Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems 

Regulación del Ciclo Celular y la Diferenciación en los Sistemas Cardiovascular y Neuronales 

By Antonio Giordano, Umberto Galderisi

•Publisher:   Springer

•Number Of Pages:   300

•Publication Date:   2010-10-02

•ISBN-10 / ASIN:   160327152X

•ISBN-13 / EAN:   9781603271523

Product Description:

Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.

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Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair: From Basic Research to Clinical Applications

 

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair: From Basic Research to Clinical Applications

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Biología Molecular de los receptores y de los transportadores: Receptores - Molecular Biology of Receptors and Transporters: Receptors

Molecular Biology of Receptors and Transporters: Receptors - Biología Molecular de los receptores y  de los transportadores: Receptores

Publisher: Academic Press | ISBN: 0123645387 | edition 1993 | PDF | 285 pages | 13,6 mb

Este libro habla de la biología molecular de los receptores y los transportadores celulares. Un tema muy interesante cuando estudiamos la célula. El sistema de proteínas G y otras involucradas.

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Origin of Cancers: Clinical Perspectives and Implications of a Stem-Cell Theory of Cancer - Origen del cáncer: Perspectivas clínicas y las consecuencias de una Teoría del Cáncer por una stem-cell

Shi-Ming Tu, "Origin of Cancers: Clinical Perspectives and Implications of a Stem-Cell Theory of Cancer" -

Origen del cáncer: Perspectivas clínicas y las consecuencias de una Teoría del Cáncer  por una stem-cell

Springer | 2010 | ISBN: 144195967X | 237 pages | PDF | 1,7 MB

La teoría del origen de cáncer en una stem cell  no es nada nuevo. Muchos destacados investigadores han establecido las bases para este concepto y realizaron experimentos vitales para apoyar su validez y mérito. El objetivo de este libro es ilustrar cómo esta teoría puede transformar completamente nuestra opinión actual  y perspectiva sobre el cáncer. Se prevé que la variedad de ramificaciones de un stem-cell originadora de cánceres será adoptada por la comunidad de investigadores en medicina  para llevar nuevas modalidades de tratamiento a los pacientes con cáncer.

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The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation by Gajanan V. Sherbet - La Genética del Cáncer: Genes asociados con la invasión del cáncer, Metástasis y proliferación celular

The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation by Gajanan V. Sherbet - La Genética del Cáncer: genes asociados con el cáncer invasión, Metástasis y proliferación celular 

Publisher: Academic Press; 1st edition (July 11, 1997) | ISBN: 0126398755 | Pages: 338 | PDF | 26.45 MB

Escrito por expertos reconocidos a escala internacional, La Genética del Cáncer proporciona información actualizada y comprensión de las bases genéticas del cáncer y de los mecanismos involucrados en la invasión del cáncer y de su diseminación secundaria. Este volumen presenta la desregulación del ciclo celular en el desarrollo del tumor e integra la función de los genes supresores de tumores (GST), oncogenes, y los genes asociados a las metástasis en la patogénesis y progresión del cáncer. La Genética del Cáncer será de utilidad para todos los  estudiantes graduados, clínicos e investigadores que trabajan en los campos de la biología del cáncer, genética y biología molecular.

Puntos Clave: El contenido incluye:

• Evolución clonal del fenotipo metastásico.
• Regulación del Ciclo Celular.
• Apoptosis en el Crecimiento Tumoral y en la metástasis.
• Angiogénesis en el cáncer.
• Glicoproteínas de la superficie celular y sus receptores.
• Proteinasas y sus inhibidores en la etapa de invasión por parte del cáncer.
• Oncogenes y metástasis cancerígena.
• Genes del desarrollo.
• Genes Supresores de Tumores (GST).
• Genes Supresores de Metástasis.
• Genes dominantes asociados a las metástasis.

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