jueves, 31 de diciembre de 2009

RNA Purification and Analysis: Sample Preparation, Extraction, Chromatography - ARN Purificación y Análisis: Preparación de la muestra, extracción, Cromatografía

Douglas T. Gjerde, Lee Hoang, David Hornby, "RNA Purification and Analysis: Sample Preparation, Extraction, Chromatography"
"ARN Purificación y Análisis: Preparación de la muestra, extracción, Cromatografía"
Wiley-VCH | 2009 | ISBN: 3527321160 | 206 pages | PDF | 2,3 MB
The complete know–how on optimizing lab protocols for handling every RNA species –– from the very small to the very large.
In contrast to DNA, which is restricted to the single function of carrier of genetic information in the cell nucleus, RNA –– a closely related but biochemically very different molecule, is employed in a variety of functions. Consequently, there are dozens of functionally different RNA classes in the cell. Their analysis and selective enrichment requires special knowledge and special tools, many of which have been substantially improved in recent years.
This is the first book on the market to cover the many new and important RNA species discovered over the past five years, and it explains current methods for their enrichment, separation and purification.
Building up from general principles of RNA biochemistry and biophysics, it addresses the practical aspects relevant to the laboratory researcher throughout, while discussing the performance and potential problems of the methods discussed.
From the contents:
∗ The need for RNA extraction, analysis and purification
∗ RNA solid phase extraction and chromatography
∗ Extraction and sample preparation of RNA
∗ Applications of RNA chromatography
∗ siRNA and miRNA: Analysis, purification and use
An appendix contains a glossary with the important terms and techniques used in RNA analysis.
By explaining the basic and working principles of the methods, the book allows biochemists and molecular biologists to gain much more expertise than by simply repeating a pre–formulated protocol, enabling them to select the procedure and materials best suited to the RNA analysis task at hand. As a result, they will be able to develop new protocols where needed and optimize and fine–tune the general purpose standard protocols that come with the purification equipment and instrumentation.
Enlaces funcionales. Functionals links.

Advances in the Management of Testosterone Deficiency (Frontiers of Hormone Research) - Avances en el manejo de la deficiencia de testosterona (Fronteras en la Investigación de hormonas)


T. Hugh Jones "Advances in the Management of Testosterone Deficiency (Frontiers of Hormone Research)"
"Avances en el manejo de la deficiencia de testosterona (Fronteras en la Investigación de hormonas)"
S. Karger AG | English | 2008-11-30 | ISBN: 3805586221 | 209 pages | PDF | 1,9 MB
Testosterone has an important influence on major organ systems and tissues, including brain, metabolism, cardiovascular as well as musculoskeletal and immune systems. Covering many clinical areas, this book pays particular attention to the diagnosis and management of hypogonadism, discussing current guidelines, biochemical assessment, new options in testosterone replacement therapy and long-term monitoring of treated men. Furthermore the role of testosterone deficiency in aging, obesity, muscle function and frailty and erectile dysfunction is covered.Recent evidence for the role of testosterone in the pathogenesis of chronic diseases such as diabetes, cardiovascular disease and osteoporosis is reported. New developments in the potential treatment of these clinical conditions are also. presented. Primarily of interest to endocrinologists, urologists, andrologists and sexologists, the range of topics covered is also relevant to primary care physicians, gerontologists, diabetologists and cardiologists.
Enlaces funcionales. Functionals links.

sábado, 26 de diciembre de 2009

Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment - Resistencia a la insulina y PCOS: Patogénesis, Evaluación y tratamiento

Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali, "Insulin Resistance and Polycystic Ovarian Syndrome (PCOS): Pathogenesis, Evaluation, and Treatment"

"Resistencia a la insulina y síndrome de los ovarios poliquísticos (PCOS): Patogénesis, Evaluación y tratamiento"
Humana Press | 2007 | ISBN: 1588297632 | 487 pages | PDF | 57,1 MB
Despite dizzyingly fast-paced advances over the past two decades, even the definition of Polycystic Ovarian Syndrome (PCOS) remains in dispute. Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment highlights the recent transition of PCOS from an infertility disorder with a diagnosis based on ovarian tissue histology to a more complex clinical entity, a metabolic disorder in which insulin resistance plays a central role. With an expert panel of authors, each chapter provides an up-to-date and balanced overview of PCOS, paying special attention to the central role of insulin resistance in the syndrome’s pathogenesis and in the management of its reproductive and metabolic abnormalities.
Comprehensive and thought-provoking, Insulin Resistance and Polycystic Ovarian Syndrome: Pathogenesis, Evaluation, and Treatment is an invaluable resource for endocrinologists, gynecologists, and internists eager to learn more about this controversial and challenging disease.

viernes, 25 de diciembre de 2009

Gastrointestinal Microbiology - Microbiología Gastrointestinal

 Aquí una entrega del libro Microbiología Gastrointestinal.

Archivo sin contraseña - without a password 
descargar = download
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sábado, 19 de diciembre de 2009

Lippincott Williams & Wilkins Atlas of Anatomy - Lippincott Williams & Wilkins Atlas de Anatomía


Lippincott Williams ; Wilkins Atlas of Anatomy
          By Patrick W Tank, Thomas R Gest
"Lippincott Williams & Wilkins Atlas de Anatomía"
Publisher: Lippincott Williams & Wilkins | 2008 | 448 Pages | ISBN: 0781785057 | CHM | 25.05 MB
Featuring more than 750 new, modern images, the Lippincott Williams & Wilkins Atlas of Anatomy is a vibrantly colored regional atlas of human anatomy offering an unprecedented combination of visual aesthetic appeal and anatomical accuracy. Many student-friendly features set this atlas apart from others on the market, including a unique art style featuring bright colors, color coding of anatomical elements, judicious use of labeling, and no extraneous text. Each plate is designed around a teaching/learning objective, providing immediate focus and resulting in easier and faster comprehension. This unique pedagogy, in combination with the atlas' beautiful art style, will make this new anatomy atlas the preferred choice of teachers and students alike. Packaged with the atlas is an online interactive atlas with all of the images, including fully searchable legends and labels and "zoom-and-compare" features. Also included are electronic flash cards that permit students to test their knowledge of newly learned concepts and structures.

Heat Shock Proteins in Cancer - Proteínas de Choque Calorífico (hsp) en el Cáncer


Stuart K. Calderwood, Michael Y. Sherman (Editor), Daniel R. Ciocca (Editor) "Heat Shock Proteins (hsp) in Cancer"
"Proteínas de Choque de calor o de choque calorífico (hsp) en el cáncer"
Springer | English | 2007-10 | ISBN: 1402064004 | 406 pages | PDF | 5,2 MB
Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Enlaces funcionales. Working and living links.

domingo, 13 de diciembre de 2009

Medical Microbiology, 3ª edition, Cedric Mims - Microbiología Médica 3ª Edición


Cedric Mims, Hazel Dockrell, Richard Goering, Ivan Roitt, Derek Wakelin, Mark Zuckerman "Medical Microbiology, 3ª  edition"
Microbiología Médica 3ª Edición , Cedric Mims
Mosby | English | 2004-11-18 | ISBN: 0323035752 | 660 pages | CHM | 77,7 MB
Medical Microbiology has been improved and updated to keep it at the forefront of microbiological teaching practice. The clinically relevant, systems-based approach has been retained so as to emphasise the microbiology of the agents causing disease and the diseases affecting individual organ systems.
Over 250 color diagrams explain difficult concepts while color clinical photographs appear alongside the microbiology, stressing the clinical relevance of the science.
This book opens with an expanded basic introduction to viruses, bacteria, fungi and parasites. Then the immunology of the host is considered (again in more detail than in previous editions) before looking at the complex conflicts between host and invading agent. The clinical manifestations of these conflicts are explored within a systems-based context before concluding with a re-organised survey of microbiological diagnosis and control.
Throughout, attractive design features are used to highlight core information and make study and review that bit easier: Chapter Introductions, Key Facts Boxes, case-based Review Questions, new Microbiology Lessons and Summary Headings throughout make Medical Microbiology a pleasure to read. 
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2ª edición en Castellano (pdf):
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Current Trends in Monoclonal Antibody Development and Manufacturing, Vol. XI (Biotechnology: Pharmaceutical Aspects)


Steven J. Shire, Wayne Gombotz, Karoline Bechtold-Peters, James Andya "Current Trends in Monoclonal Antibody Development and Manufacturing, Vol. XI (Biotechnology: Pharmaceutical Aspects)"
Springer | English | 2009-11-12 | ISBN: 0387766421 | 354 pages | PDF | 5,5 MB
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade.
Recently the regulatory review of monoclonal antibodies has been moved from Center for Biologics and Research to the Center for Drug Evaluation and Research (CDER) division of the US Food and Drug Administration. It is anticipated that CDER will expect a certain minimal amount of data to be provided as more of these products move through the regulatory pipeline. Current Trends in Monoclonal Antibody Development and Manufacturing will provide readers with an understanding of what is currently being done in the industry to develop, manufacture, and release monoclonal antibody products and what will be required for a successful regulatory submission.

Latin American Insects and Entomology by Charles L. Hogue - Insectos Latinoamericanos y Entomología


Charles L. Hogue, "Latin American Insects and Entomology -
"Insectos Latinoamericanos y Entomología"
University of California Press | 1993 | ISBN: 0520078497 | 594 pages | PDF | 10,9 MB
This is the first comprehensive guide to insect life in a part of the world known for its abundant, and endangered, life forms. Charles Hogues scholarship embraces vast geographical territoryMexico, Central and South America, and the Caribbean. Color photographs and first-rate drawings illustrate the clearly written text.
I was first recommended this book nearly ten years ago when working on a Venezuela field course for the University of California, Pomona. I had never heard of it, but one of the entomology professors assured me that it was the best available resource on Neotropical entomology - she was right! Given the dearth of identification materials on Latin American insects, this tome steps in to fill the breach as well as any single volume can. It is a useful introduction to the natural history of tropical insects and can also be used as a rough field guide allowing one to identify most insects to order, often to family and sometimes even to genus and species. In the absence of other books, this is the volume that students and amateurs should choose. The price is certainly a deterrent, but it's often available used. I have been using my well-tuhumbed copy in and out of the field for quite a few years so it has earned its keep!
Summary: It's a good book.
Very complete book. Describes most groups, and the arthropods you are most likely to find. Not too technical, great for explaining to people what they are looking at. The 2 problems I can see with it, are the cost (although I do not mind paying for quality in the least, which is why I bought it and highly recommend it) and that being a general guide it sometimes does not go into as much depth as I would like. Still, I rate it as an awesome book!
Summary: a unique book on Latin American insects
This book by the late Dr. Hogue fills a needy slot in Latin American natural history by combining scientific detail with a simple, clear presentation of Latin America's many insect groups. Each group is discussed in turn with summries of taxonomy, diversity and natural history. Basic but useful black and white illustrations give one a "feel" for each of these group. While this is no field guide to identification, it is an excellent overview of information that is otherwise scattered through the literature. We use it at our field site in South America and the only complaint is that there is no Spanish translation! (¡La única queja es que No hay una traducción al castellano y al portugués!)

mediadescarga aquí

sábado, 12 de diciembre de 2009

Urinalysis and Body Fluids - Análisis de orina y fluidos corporales - Enlaces Actualizados


Urinalysis and Body Fluids
By Susan King Strasinger, Marjorie Schaub Di Lorenzo

"Análisis de orina y fluidos corporales"
* Publisher: F. A. Davis Company
* Number Of Pages: 292, PDF | 36 MB
* Publication Date: 2008-02-15
* ISBN-10 / ASIN: 080361697X
* ISBN-13 / EAN: 9780803616974
Product Description:

This thoroughly updated 5th Edition provides concise and carefully structured full-color instruction in the handling and analysis of non-blood body fluids.Readers will learn how to handle and preserve the integrity of body fluid specimens and how to keep themselves and their laboratory safe from infectious agents!Practical, focused, and reader friendly, this popular text teaches the theoretical and practical knowledge every clinical laboratory scientist needs to handle and analyze non-blood body fluids, and to keep them and their laboratory safe from infectious agents. The 5th Edition has been completely updated to include all of the new information and new testing procedures that are important in this rapidly changing field. Case studies and clinical situations show how work in the classroom translates to work in the lab.The body fluids chapters are expanded to include additional anatomy, physiology, and recent advances in testing. It provides significantly enhanced coverage of body fluids, amniotic fluid, feces, CSF, and metabolic diseases, particularly in the areas of anatomy and physiology, function, and recent advances in testing. It uses case studies and clinical situations to promote problem-solving and critical-thinking skills. It features more than 175 full-color slides of urine, cerebrospinal, seminal, synovial, and serous fluids, positioned close to the related text. It reviews renal physiology and renal function testing. It offers comprehensive discussions of the physical, chemical, and microscopic analyses of urine. It covers quality assurance and management, including requirements of accrediting agencies. It uses procedure and summary boxes for quick reference. It includes a comprehensive discussion of current instrumentation in the urinalysis laboratory.
Enlaces funcionales. Working and living links.
Enlace del libro Strasinger Di Lorenzo Urinalysis and Body Fluids (Análisis de Orina Y de los Líquidos Corporales) (en 2 versiones, tradicional (1) y optimado con ocr y bookmark (2) pronto):

  1.     ultradescarga aquí no opt.
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Fungi: Experimental Methods In Biology (Mycology) - Hongos: Métodos Experimentales de Biología (Micología)

Fungi: Experimental Methods In Biology (Mycology)
Hongos: Métodos Experimentales de Biología (Micología)

Publisher: CRC, Number Of Pages: 264, Publication Date: 2005-06-23, ISBN / ASIN: 1574444689, Binding: Hardcover, format: pdf


Book Description:
Presenting information generated through the application of genetics, molecular biology, and biochemistry, this book analyzes information derived through real experiments, and focuses on unresolved questions in the field. The text describes the special features of fungi, interactions of fungi with other organisms, model fungi in research, gene manipulation, adaptations, and natural populations. Each stand-alone chapter enables the reader to progress from elementary concepts to advanced research, benefiting both beginning research workers and experienced professionals. A comprehensive appendix covers the principles in naming fungi and discusses their broad classification.

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Clinical Lipidology: A Companion to Braunwald's Heart Disease - Lipidología Clínica: Un acompañante del libro Braunwald's Heart Disease


Christie M. Ballantyne MD "Clinical Lipidology: A Companion to Braunwald's Heart Disease"
"Lipidología  Clínica: Un acompañante del libro Enfermedad Cardiaca de Braunwald"

Saunders | English | 2008-12-09 | ISBN: 1416054693 | 608 pages | PDF | 32 MB
Dr. Ballantyne-one of the foremost lipid experts in the world and recruited by Dr. Braunwald's Heart Disease editorial team-together with a stellar cast of contributors provides all of the scientific and clinical information you need to effectively manage every aspect of dyslipidemia. From basic science to pathogenesis of atherothrombotic disease. Actualizado
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Atlas de Hematología Mc Donald 5ª edición en castellano

atlas-de-hematologia



Teniendo en mente esta finalidad, se incluyen los aspectos normales de la sangre y la médula ósea con fines comparativos, no solo en toda la obra sino en un esquema de maduración aparte. Tambien se representan los tejidos normales, dispuestos en íntima proximidad con las ilustraciones de los estados patológicos de los mismos órganos.

Atlas de Hematología Mc Donald
Quinta Edición en castellano
Este Atlas tiene como finalidad la de ilustrar el aspecto microscópico de los diversos trastornos hematológicos, no solamente los medulares o los de sangre periférica sino los observados en los órganos afectados en enfermedades hematológicas.

Fisiología Humana Houssay

fisiologia humana.jpeg

Contiene
- Fisiología General.
- Sistema digestivo.
- Sistema circulatorio.
- Sistema respiratorio.
- Riñón y electrolitos.
- Metabolismo y endocrinología.
- Reproducción.
- Neurofisiología.etc

Fisiología Humana Houssay
Alberto B. Houssay
Horacio E Cingolani
7a Edición
Fisiología Humana Houssay es un clásico de la medicina, se ha renovado totalmente de acuerdo con los últimos conocimientos, con la participación de 50 coautores de distintas universidades, quienes presentan en los diversos capítulos de esta ciencia básica, su amplia experiencia en la docencia y en la investigación, con una redacción sucinta y didáctica, apoyada por numerosas ilustraciones. Este es un texto destinado a los estudiantes y a los profesionales que deseen estudiar los principios fundamentales de la fisiología moderna. La fisiología, es la más interdisciplinaria de las ciencias médicas. Su dominio es imprescindible para la adecuada comprensión de los procesos normales y patológicos.
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viernes, 11 de diciembre de 2009

Inmunología celular y molecular Abbas 3° edicion en Castellano


 
Inmunología  celular y molecular de Abbas 3ª edición en castellano



Autores: Abbas, Lichtman, Pillai; Formato: PDF; 3ªedición; Castellano.
La 3ª edición del libro Inmunología bastante consultada por diversos lectores de diversas ramas de la salud.  La obra, que recoge los últimos avances en la materia, se presenta como una guía excepcional tanto por su contenido estructurado y actualizado como por su magnífica ilustración, explicando claramente las bases de la inmunología a nivel molecular, celular y de todo el organismo en su conjunto. - Es el material de aprendizaje fundamental de la asignatura que se imparte como troncal en las licenciaturas de Medicina, Farmacia, Veterinaria, Bioquímica y odontología.
(Reposteado de la biblioteca médica, por pedido de un visitante GRACIAS A LA BIBLIOTECA MEDICA.) Fragmentado en dos partes alojadas en dos sitios (intercambiables):
Parte1: Egodescarga aquí parte 1 , RSdescarga aquí parte 1
Parte2:
Egodescarga aquí parte 2 , RS descarga aquí parte 2

Inmunología Celular y Molecular Abbas 6ª Edición en Castellano



Título: Inmunología Celular y Molecular
Inmunología Celular y Molecular Abbas 6ª Edición en Castellano
Autores: Abbas, Lichtman, Pillai; Formato: PDF; 6ª edición; Castellano; 552 páginas; Tamaño: 55 Mb

6a edición de la obra reconocida internacionalmente como el best seller de la inmunología, constituyendo una referencia clásica con la que se han formado numerosas generaciones de estudiantes. - La obra, que recoge los últimos avances en la materia, se presenta como una guía excepcional tanto por su contenido estructurado y actualizado como por su magnífica ilustración, explicando claramente las bases de la inmunología a nivel molecular, celular y de todo el organismo en su conjunto. - Es el material de aprendizaje fundamental de la asignatura que se imparte como troncal en las licenciaturas de Medicina, Farmacia, Veterinaria y odontología.
(Reposteado de la biblioteca médica, por pedido de un visitante GRACIAS A LA BIBLIOTECA MEDICA.)

Pancreatic Beta Cell in Health and Disease - Las Células Beta Pancreáticas en la Salud y en la Enfermedad


Susumu Seino, Graeme I. Bell, "Pancreatic Beta Cell in Health and Disease"
"Las Células Beta Pancreáticas en la Salud y en la Enfermedad"
Springer | 2007 | ISBN: 4431754512 | 200 pages | PDF | 6 MB
The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis, regulating glucose uptake in muscle and adipose tissue as well as carbohydrate, fat, and protein metabolism in these tissues and the liver.
This book provides a comprehensive up-to-date review of the beta cell in health and disease. Chapters address the architecture and pathology of normal and diabetic pancreatic islets; regulation of beta-cell proliferation and death; the potential of stem cells and extra-pancreatic tissues as beta-cell replacement therapies; insulin biosynthesis; regulation of insulin secretion including metabolic control, ion channels, gap junctions, cyclic AMP, incretins, and exocytosis; development of novel imaging techniques; and genetic disorders of the beta cell. A primary aim of the book is to encourage students and young basic and clinical investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.
Enlaces funcionales. Working and living links.
MEGADESCARGA AQUÍ
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The Dopamine Receptors (2009) - Los Receptores de Dopamina (2009)


The Dopamine Receptors
Los Receptores de Dopamina (2009)
Publisher: Humana Press | Language: English | ISBN: 1603273328 | 648 pages | Data: 2009 | PDF | 7 Mb
Description: As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.
Enlaces funcionales. Working and living links.
updescarga aquí
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lunes, 7 de diciembre de 2009

Semiología Médica Integral de Yuluka 1ª edición

semiologia-de-yuluka

Semilogía Médica Integral de YULUKA , Edición: 1ª
Semiología médica integral primera edición, es un compendio básico, conciso, completo y con más de 800imágenes en el que se explican la historia clínica desde el punto de vista legal; así como la inspección, la palpación, la percusión, la auscultación, es decir, los métodos semiológicos de exploración
Se incluyen capítulos dedicados a la semiología básica de los principales órganos, sistemas y sentidos entre los cuales están el cardiovascular, el respiratorio, el genitourinario, el gastrointestinal; también, dedica capítulos a la evaluación semiológica del niño sano, la mujer embarazada, el anciano sano y de los deportistas; así mismo, concilia el método clínico con la tecnología creciente, incluyendo capítulos como imagenología del sistema nervioso central, del tórax, del abdomen, la pelvis, el sistema genitourinario y del sistema óseo, en los cuales se parte de una descripción representativa de las imágenes normales.
RSdescarga aquí

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nakidescarga aquí en rar el yuluka

Semiología Médica de Goic

Un fabuloso y clásico libro de semiología al alcance de nuestras manos. Todo aquel que necesite información sobre semio tendría que leer este libro. Es junto con otros uno de los pilares de la semiología.





domingo, 6 de diciembre de 2009

Signaling Pathways in Liver Diseases - Caminos Señalizados en Enfermedades del hígado


Signaling Pathways in Liver Diseases
 Caminos Señalizados en Enfermedades del hígado
Springer | 2010-01 | ISBN: 3642001491 | 578 pages | PDF | 9 MB
Signaling Pathways in Liver Diseases, 2nd edition focuses on signaling pathways which are particularly important in liver diseases. Recent progress brought hepatology to new frontiers. The increasing frequency of surgery on steatotic and cirrhotic liver obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations and how they can be influenced. Better comprehension of the cellular mechanisms participating in liver regeneration, hepato-cellular apoptosis and ischemia/reperfusion inquiry is mirrored by a dramatic increase in complexity. The number and scope of publications is intimidating and difficult for busy individuals to extract a coherent framework. This book will serve as a source of information facilitating the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets for novel therapeutic strategies. It will furthermore stimulate more research and lead to better exchange between the laboratory, the clinical ward and the operation room.
file2Descarga aquí
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Stem Cell Therapy for Diabetes (Stem Cell Biology and Regenerative Medicine) - Terapia con células madre para la Diabetes (Biología de células madre y medicina regenerativa)

Stem Cell Therapy for Diabetes (Stem Cell Biology and Regenerative Medicine)
Terapia con células madre para la Diabetes (Biología de células madre y medicina regenerativa)
Humana Press | 2009-12-04 | ISBN: 1607613654 | 291 pages | PDF | 3 MB
Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Sure to pique the interest of investigators, clinicians, and students of stem-cell application in regenerative medicine, and cell therapy of diabetes, Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.
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Internal Medicine Just the facts, Paul G. Schmitz, MD, FACP & Kevin J. Martin - Medicina Interna Sólo los hechos

Internal Medicine Just the facts 
Medicina Interna Sólo los hechos 
Paul G. Schmitz, MD, FACP & Kevin J. Martin, MB, BCh, FACP
| English | ISBN: 0071593438 | 2008 | PDF | 810 pages | 7.47 Mb
All the essentials of internal medicine in an instant! This concise, yet all-inclusive review is the perfect tool to prepare for primary certification and recertification exams, or for use as a clinical refresher. Its streamlined format conveniently condenses and simplifies the most important content, for maximum yield and comprehension- making it indispensable for internal medicine residents, clerkship students, and busy practitioners.

Illustrated Textbook of Paediatrics By Tom Lissauer, Graham Clayden - Texto Ilustrado de Pediatría




Illustrated Textbook of Paediatrics
By Tom Lissauer, Graham Clayden
Texto Ilustrado de Pediatría
Publisher: Mosby; 3 edition | 2007 | 528 Pages | ISBN: 0723433976 | CHM | 107.84 MB
A concise, colourfully illustrated and highly informative textbook of paediatrics. Written primarily for medical students for their course in clinical paediatrics (6-10 weeks in duration in the UK and worldwide), the book has found a wider audience among nurses, trainee paediatricians preparing for the MRCPCH, and general practitioners preparing for the DCH. Throughout, there is an emphasis on the core fundamentals of paediatrics practice throughout the world, which has contributed to its success in Europe, Asia, Australia and the Middle East.

* In the book:
o Summary boxes to help learning/revision
o Additional diagrams and photographs to assist learning
o Bringing book up to date and expanding topical items such as immunisations, obesity, child protection, ethics, medicines in children
o New chapters on Allergy and Adolescent Medicine
o Improved navigation by means of: Chapter summaries at the beginning of chapters using main headings and page numbers
o Colour-coding of chapters
o Differentiation of types of boxes by colour and numbering

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Introduction to Medical Immunology - Introducción a la Inmunología Médica


Introduction to Medical Immunology
Introducción a la Inmunología Médica
Publisher: Informa HealthCare | ISBN: 082479897X | edition 1998 | PDF | 711 pages | 8,87 mb
Medical Univ. of South Carolina, Charleston. Introductory textbook for medical students integrating basic and clinical science. This edition is written in outline format. 14 U.S. contributors. DNLM: Immunity.

Human Growth Hormone: Research and Clinical Practice (Contemporary Endocrinology) Roy G. Smith, Michael O. Thorner - "Hormona del Crecimiento Humana (GH, Somatotrofina): Investigación y Práctica Clínica (Endocrinología Contemporánea)"


Roy G. Smith, Michael O. Thorner "Human Growth Hormone: Research and Clinical Practice (Contemporary Endocrinology)"
"Hormona del Crecimiento Humana (GH, Somatotrofina): Investigación y Práctica Clínica (Endocrinología Contemporánea)"
Humana Press | English | 2000-02-15 | ISBN: 0896035050 | 348 pages | PDF | 4,3 MB
In a state-of-the-art synthesis of basic science and clinical practice, Roy Smith and a distinguished panel of researchers and clinicians review GH regulation and its action at the molecular level, and describe the basis for GH deficiency and the use of GH as therapy in a variety of clinical situations. The clinical presentation moves beyond the treatment of GH-deficient children to include the genetics of GH-deficiency, GH-deficiency in adults, osteoporosis, Syndrome X, sleep quality, GH in AIDS patients, GHRH in clinical studies. Timely and innovative, Human Growth Hormone: Research and Clinical Practice will benefit both basic and clinical researchers, as well as those clinical endocrinologists who want to use growth hormone not only in treating children, but also in treating adult disorders, including those associated with metabolic disease.
Los links funcionan bien al momento de postear. The links work well at the time of post.

Drugs in Use, 4th Edition, Linda J. Dodds - Drogas en uso, 4ª Edición

Linda J. Dodds, "Drugs in Use, 4th Edition" 
Drogas en uso, 4ª Edición
Pharmaceutical Press | 2009 | ISBN: 0853697914 | 666 pages | PDF | 2,3 MB
This revised fourth edition of "Drugs in Use" presents a series of clinical case studies to illustrate how pharmacists can optimise drug therapy in response to the needs of individual patients. Patient information is interspersed with questions and answers suitable for self-study or group discussion and a pharmaceutical care plan is included within each chapter. The cases included address situations which are commonly encountered or associated with particular difficulties in treatment individualisation. Those in which major advances in therapeutics have recently occurred are also covered. All case studies from the previous edition have been updated and revised, and new chapters have been included on the following: eczema; psoriasis; Crohn's disease; oncology; and, substance misuse. Translating the knowledge acquired during undergraduate and postgraduate pharmacy courses into the clinical skills required to optimise the therapy of patients can seem a daunting task. This book was conceived as a method of helping pharmacists and prescribers to 'bridge the gap' between the acquisition of theoretical knowledge about drugs and its practical application to individual patients. It will be an invaluable resource for pharmacy students, pre-registration pharmacists and practising pharmacists. It will also be a valuable resource for medical students and non-medical prescribers.

Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability - Biodisponibilidad de las Drogas: Estimación de la solubilidad, permeabilidad, absorción y Biodisponibilidad

Han van de Waterbeemd, Bernard Testa, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, "Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability"  Biodisponibilidad de las Drogas: Estimación de la solubilidad, permeabilidad, absorción y Biodisponibilidad
Wiley-VCH | 2008 | ISBN: 3527320512 | 649 pages | PDF | 4,4 MB
The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.
In 21 chapters readers can benefit from the key working knowledge of today′s leading pharmaceutical companies, including Pfizer, AstraZeneca, and Roche. Drug developers from industry and academia present all the factors governing drug bioavailability, complete with practical examples and real–life data.
Part I focuses on in vitro and in vivo measurements of physicochemical properties, such as membrane permeability and ionization. Part II discusses solubility and gastrointestinal absorption, while the third part is devoted to metabolism and excretory mechanisms. The much revised and expanded part IV surveys current in silico approaches to predict drug properties needed to estimate the bioavailability of any new drug candidate. The final part shows how poor bioavailability may be improved by various approaches during the development process.
No other publication offers the same level of treatment on this crucial topic in modern drug development.
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Transporters as Drug Carriers: Structure, Function, Substrates (Methods and Principles in Medicinal Chemistry) - Transportistas como transportadores de drogas: estructura, la función, Sustratos (Métodos y principios de la Química de Medicamentos)

Gerhard Ecker, Peter Chiba, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers "Transporters as Drug Carriers: Structure, Function, Substrates (Methods and Principles in Medicinal Chemistry)"
Transportistas como transportadores de drogas: estructura, la función, Sustratos (Métodos y principios de la química de medicamentos)
Wiley-VCH | English | 2009-12-14 | ISBN: 3527316612 | 449 pages | PDF | 5 MB
This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion.
As a result, this key resource lays the foundations for understanding and investigating the molecular mechanisms for multidrug resistance in cancer cells, microbial resistance to antibiotics and pharmacokinetics in general.
For anyone working with antibiotics and cancer chemotherapeutics, as well as being of prime interest to biochemists and biophysicists.

sábado, 5 de diciembre de 2009

Biochemistry, Fifth Ed Jeremy M. Berg, John L. Tymoczko, Lubert Stryer - Bioquímica de Stryer 5ª Edición

Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, "Biochemistry, Fifth Ed"
Bioquímica de Stryer Quinta Edición
W. H. Freeman | 2002 | ISBN: 0716798085 | 1050 pages | PDF | 25,8 MB
For more than 25 years, and through four editions, Stryer's Biochemistry has laid out this beautiful subject in an exceptionally appealing and lucid manner. The engaging writing style and attractive design have made the text a pleasure for our students to read and study throughout our years of teaching. Thus, we were delighted to be given the opportunity to participate in the revision of this book. The task has been exciting and somewhat daunting, doubly so because of the dramatic changes that are transforming the field of biochemistry as we move into the twenty-first century. Biochemistry is rapidly progressing from a science performed almost entirely at the laboratory bench to one that may be explored through computers. The recently developed ability to determine entire genomic sequences has provided the data needed to accomplish massive comparisons of derived protein sequences, the results of which may be used to formulate and test hypotheses about biochemical function. The power of these new methods is explained by the impact of evolution: many molecules and biochemical pathways have been generated by duplicating and modifying existing ones. Our challenge in writing the fifth edition of Biochemistry has been to introduce this philosophical shift in biochemistry while maintaining the clear and inviting style that has distinguished the preceding four editions.

Biosensors and Modern Biospecific Analytical Techniques (Comprehensive Analytical Chemistry): Lo Gorton

Biosensors and Modern Biospecific Analytical Techniques (Comprehensive Analytical Chemistry): Lo Gorton
Elsevier | ISBN: 0444507159 | 2005-06-01 | PDF (OCR) | 644 pages | 40.2 Mb
Biosensors and Modern Biospecific Analytical Techniques further expands the Comprehensive Analytical Chemistry series' coverage of rapid analysis based on advanced technological developments. This 12-chapter volume summarizes the main developments in the biosensors field over the last 10 years. It provides a comprehensive study on the different types of biosensors, including DNA-based, enzymatic, optical, self-assembled monolayers and the third generation of biosensors. As well as many technological developments on bioanalytical microsystems and new materials for biosensors, antibody and immunoassay developments have a prominent place in the book.
* Provides a comprehensive study on the different types of biosensors
* Applications covered include environmental analysis, bioprocess monitoring and biomedicine
* An indispensable resource for those working in analytical chemistry
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Sandy B. Primrose, Richard Twyman, Principles of Gene Manipulation and Genomics,7 Ed - Principios de la manipulación genética y de Genómica,7 Ed


Sandy B. Primrose, Richard Twyman, "Principles of Gene Manipulation and Genomics,7 Ed"
Principios de la manipulación genética y de Genómica,7 Ed
Wiley-Blackwell | 2006 | ISBN: 1405135441 | 672 pages | PDF | 4,9 MB
There has been rapid progress in recombinant DNA technology over the last few years, particularly in the area of large-scale biology (genomics and related disciplines). The increasing integration between gene manipulation and genomics is embraced in this book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis and Genomics. This important new text has been comprehensively revised, updated, and rewritten to encompass within one volume, basic and advanced gene-manipulation techniques, genome analysis, genomics, transcriptomics, proteomics, and metabolomics, as well as the applications of these fascinating technologies.
Principles of Gene Manipulation and Genomics is an accessible and up-to-date guide to this exciting field, and is the essential reference for upper-level undergraduate and graduate students of genetics, genomics, molecular biology, and recombinant DNA technology.

The Internal Medicine Casebook: Real Patients, Real Answers by Robert W Schrier -El registro de Medicina Interna: Pacientes Reales, Respuestas Reales por Robert W Schrier

El registro de Medicina Interna: Pacientes Reales, Respuestas Reales por  Robert W Schrier
The Internal Medicine Casebook: Real Patients, Real Answers by Robert W Schrier
Publisher: Lippincott Williams & Wilkins | ISBN: 0781765293 | 2007-02-01 | CHM | 496 pages | 1.7 MB
Developed by the internal medicine residency teaching staff at the University of Colorado, this book presents patient-oriented cases for 88 diseases in all areas of internal medicine. Case studies follow a question-and-answer format that mirrors rounds presentations. Each case study walks you through the workup and management of the problem and reviews the underlying pathophysiology. The book is an excellent review tool for resident in-service exams or American Board of Internal Medicine certification exams. This edition's questions and problems have been extensively rewritten to incorporate new diagnostic methods and treatments. Coverage of urology and hepatology has been expanded.

jueves, 3 de diciembre de 2009

Live Cell Imaging: Methods and Protocols (Methods in Molecular Biology)




Live Cell Imaging: Methods and Protocols (Methods in Molecular Biology)
Publisher: Humana Press | ISBN: 1607614030 | edition 2009 | PDF | 363 pages | 14,46 mb
Now a routine tool in biomedical and life science research, live cell imaging has made major progress enabling this core biochemical, cell, and molecular biology technique to become even more powerful, versatile, and affordable. In Live Cell Imaging: Methods and Protocols, a panel of expert contributors provide a comprehensive compendium of experimental approaches to live cell imaging in the form of several overview chapters followed by representative examples and case studies covering different aspects of the most current methodology. By examining a range of state-of-the-art protocols extensively validated in complex biological studies, this volume highlights new experimental and instrumental opportunities and helps researchers to select appropriate imaging methods for their specific biological questions and measurement tasks. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
Nota: Al momento de postear este libro, todos los enlaces (5) fueron revisados y funcionaban perfectamente.
Note: At the time of post this book, all links (5) were reviewed and worked perfectly. Any alteration, please,comment, likely, "the inquisitors" are working (deleting), or is a malfunction in the link or in storage site.


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